Comprehensive Pisa to Rome Travel Guide – How to travel from Pisa to Rome, Italy

Colosseum in Rome - Comprehensive Pisa to Rome Travel Guide

If you’re wondering how to get from Pisa to Rome, then this comprehensive travel guide is perfect for you!

It is no wonder that Italy has been a firm favourite European vacation spot for decades. A country rich in diversity, culture, history, and not to forget a world-famous foodie scene too. 

With destinations such as the fashionable streets of Milan, the ‘Eternal City’ of Rome, the romantic canals of Venice, historic Florence, the charming towns and villages of Puglia, or the rolling hills of Tuscany, you’ll never get bored of exploring beautiful Italy.

If you plan to visit Rome and want to combine a side trip to Pisa, then this comprehensive guide detailing the best ways of getting from Pisa to Rome will help you plan the travel logistics linked to your trip.

Tip: If you happen to be planning any other additional side trips, then you may want to read my guides on getting between Pisa and Florence, as well as between Milan and Rome too.

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Rome to Pisa Flights:

Pisa to Rome Flight Duration: Just under an hour

Catching a flight is a great way to travel from Pisa to Rome as the travel time is just under an hour. Flights depart from Pisa airport (PSA) for Rome’s Fiumicino International Airport(FCO) and are operated only by one airline, Alitalia. 

The fare on this route is roughly €87 on average and the cheapest fare, with one stop-over at Bri Bari, is €30, but takes 4 hrs and 40 minutes by Ryanair. 

Usually each day there are around 28 direct flights from Pisa to Rome. If you plan in advance, you can also get an alert set up from Skyscanner regarding any price fluctuations, whenever there is a drop or increase in the fare. 

A month view tool is the best way to find a flight provided you are flexible with the dates. I love comparing and booking through Skyscanner as they allow you to view all flight availability, times, and fares without having to browse through various airline sites. 

Click here to search and book your flights through Skyscanner. 

Trevi Fountain in Rome - Rome to Pisa train

Pisa to Rome Train:

Pisa Rome Train Journey duration: Fastest from 2-Hours 12-Minutes

Set your eyes on some of the most amazing landmarks of Italy when you next decide to travel from the historical city of Pisa to the ancient city of Rome on an exciting high-speed journey by train. 

The journey time on the Rome Pisa train route depends on the service chosen with the average time being about 3 hrs and 30 minutes to cover the 264 km long trip. Travellers need not worry about taking indirect options as not only are they equally fast but allow for a great sightseeing experience of the picturesque countryside.

The fastest Frecciabianca journey takes just 2hrs and 12 minutes, while the slower Intercity option which involves a brief layover at Firenze Santa Maria Novella railway station in Florence, may take up to four hours by local train. 

With services on this Rome to Pisa train route running from early morning to late night, you can pick any time convenient to you, to undertake the journey and enjoy high-quality services onboard.

Pisa to Rome by Train: Services:

When taking the train from Rome to Pisa there are as many as 4 departures every hour at peak times and one every 2-3 hours during the off-peak hours, thus resulting in about 50 trips per day. 

There is only one train operator plying on this route namely Trenitalia, the national rail operator of Italy, which offer five types of services namely the Regionale, Frecciarossa, Frecciargento and the local Intercity and Intercity Notte.

The first departure from Pisa leaves as early as 02:00 am in the morning and the last one at 22:30 pm in the night. Frecciarossa offers all its passengers the most comfort, convenience and high-quality service on all their routes. If you want to travel by the Italo network, the only option is to take a Trenitalia train from Pisa to Florence and then an Italo train from Florence to either Roma Termini or Roma Tiburtina in 1.5 hours.

Train from Pisa to Rome: Fares & Buying Tickets:

Reservations are not necessary on the Regionale trains which connect Pisa with Rome. The accommodation is standard class and is free seating. The coaches are however air-conditioned and comfortable with plenty of space for luggage.

You can board the train by getting a PNR code through an e-ticket which can be booked through a reliable site such as Omio.

The cost of a one-way fare per adult starts at about €14.90 if you book beforehand. Booking on the day of the journey can be a little expensive depending on the time of the day. Use Omio’s journey planner to find the best deals on either side of your preferred dates.

Train Stations:

When heading to Rome, Pisa Centrale is the main Pisa train station that you’ll depart from and is located 1.5 km from the city and can be accessed on foot. 

Travelling to Rome, you have the choice of three Rome train stations namely Roma Termini, Tiburtina, and Ostiense. While Roma Termini is situated in the heart of the city, the other two stations are located about 4 km away but have excellent bus connections to the city centre.

Leaning Tower of Pisa - Pisa to Rome Bus

Pisa to Rome Bus Service

Rome Pisa Bus Journey Time: Around 5-Hours 10-Minutes

If you are looking to travel to Rome from Pisa by bus, there is no better operator in the whole of Europe than FlixBus.They offer a single standard ticket option for the trip and the best deals and schedules are available online. MarinoBus is the other operator travelling on this Rome Pisa bus route.

The travel time from Pisa to Rome is roughly 5 hrs and 10 minutes, which can vary on certain days. Buses leave Pisa Autostazione Via Pietrasantina or Pisa Staz and arrive at Tiburtina station, Vaticano and Rome Termini. The earliest departure is 06:35 am whereas the last departs at 20:10 pm.

Bus from Pisa to Rome: Fares & Buying Tickets

The one-way fare per adult from Pisa to Rome is approximately €57, providing you book seven days in advance. 

Compare and book the various bus routes, times, and fares on Omio to make sure you get the best travel times to suit your travel itinerary.

Night service is also operated by MARINOBUS leaving Pisa Autostazione at 20:00 pm and arriving at Roma Tiburtina at 05:45 am with one transfer on the way at Bologna Autostazione.

Pisa to Rome by car

Driving from Pisa to Rome by Car

Distance from Pisa to Rome: Up to 370-kilometres / 230-miles depending on the route

A self-drive trip from Rome to Pisa is undoubtedly the best way to see the best of the Italian countryside. With its convenient location in the Tuscan region, Pisa is in close proximity to other major cities in Italy, including Florence and Siena. From Rome, the average travel time to cover the distance of 362 km will be around four hours non-stop.

There are three possible routes to take. To compare the route maps and estimated fuel and toll costs, compare these on the ViaMichelin site, a great resource for planning a road trip.

The A1 Autostrada is the fastest inland route but you must make the detour to Montepulciano, the famous winemaking town, which lies two hours north of Rome. Another option is the E80 coastal road with great views of the Tyrrhenian Sea.

Need to book your car rental for this Italian trip? Compare rates & book at AutoEurope, a great comparative sight that will show availability and rates for a wide selection of car rental providers.

The Roman Forum - where to stay in Rome

Where to Stay in Pisa and Rome

If you haven’t already done so – don’t forget to book your accommodation for your stay in both Rome and Pisa. Here are a few recommended options that would be a great addition to your Italian travel itinerary!

Rome Hotels:

Rome has a fantastic selection of great areas and neighbourhoods to consider staying in when visiting the ‘Eternal City’. Thankfully, choosing where to stay in Rome needn’t be any hassle. Consider these top picks for your next trip. 

A fabulous hotel choice located nearby to the ever-popular Colosseum is the Otivm Hotel. The Hotel Vilon is another great choice, as is the Hotel S. Anna which is located conveniently close by to the Vatican City too!

Alternatively – click here for a wider range of hotels, apartments, hostels, and guest houses that you could book for your overnight stay in Rome!

Pisa Hotels:

For the perfect home base in Pisa, consider these great accommodation options.

The beautiful Palazzo Cini Luxury Rooms in Pisa is perfect for those in search of a bit of luxury. On the other end – for travellers on a budget, consider booking the Hotel Di Stefano.

A fantastic guest house option is the Rinascimento Bed & Breakfast, whilst the Relais Pacinotti Apartments and Suites is ideal for travellers who prefer an apartment-style accommodation option. 

For a wider selection of hotels, hostels, apartments, and more – click here to search and book your Pisa accommodation.

Pisa old street - what to do in Rome and Pisa

What To Do – Rome & Pisa Tours & Activities

I always suggest booking a couple of unique activities and tours that will allow you to get to know the destination you’re visiting a little bit better. Check out these awesome tour options in both Rome and Pisa. 

Rome Tours & Activities:

Visiting Rome for 2-Days or less? If you’re stretched for time then this Rome Hop-On Hop-Off Bus Tour is the best way to see all the cities top Italian sites in a short amount of time, allowing you to focus on those you’d like to return to later. 

History buffs should most definitely get your hands on your own entry tickets to the Colosseum & Roman Forum, and also the Skip-The-Line entry ticket to the Vatican Museums and the Sistine Chapel.

Want to learn to cook the Italian way? In this 2.5-Hour Pasta Making Class, you’ll be guided by a local chef on how to make the perfect Italian pasta. A great way to savour the authentic flavours of Italy!

Click here if you’re looking for more exciting tours and activities in Rome!

Pisa Tours & Activities:

The Leaning Tower of Pisa is undoubtedly one of the most iconic sights in Italy. A visit to Pisa simply wouldn’t be complete with exploring it. Consider booking this Fully Inclusive and Guided Tour of the Baptistery, the Cathedral, and the Tower.

Food-lovers will delight in this 3.5-Hours Food Tour of Pisa that will take you through 5 foodie spots in Pisa and allow you to taste a variety of traditional Italian foods. Don’t forget to grab an authentic Italian drink and savour all the delights of Pisa!

Click here for an awesome selection of experiences and tours in Pisa.